In March 2009, iSeek became a client, marking the beginning of another long-term business relationship. The following year, iSOS began working with Scott Fraser Training, a partnership that has endured to the present day. 2011 saw further expansion of the client base with Gearing Media coming on board, as well as the start of significant projects for Brighton University and other educational institutions.

A major milestone came in November 2015 when iSOS created an iPad Pro demo solution for Claris FileMaker. This project showcased the company's innovative approach and technical expertise. Around this time, iSOS also became one of the first UK developers approved by Xero for integration work, further cementing its reputation in the industry.

Throughout its history, iSOS has worked on projects for major companies, including Nike, Sky, and Virgin Atlantic. The company has also developed strong relationships in the education sector, creating solutions for various universities such as the University of Westminster, University of Brighton, University of Columbia (NY), Arts University of Bournemouth, University of Portsmouth, and University of Chichester.

As technology has evolved, so has iSOS. The company has consistently adapted to new technologies and client needs, focusing on creating innovative solutions across various industries. In recent years, iSOS has begun to emphasise partnerships with clients to develop products for wider industries. Most recently, the company has started working on AI solutions, including sandboxed AI systems for enterprise clients, demonstrating its commitment to staying at the forefront of technological advancements.

Throughout its history, iSOS has maintained long-term relationships with many clients, some dating back to its founding in 2006. This longevity is a testament to the company's dedication to client satisfaction and its ability to provide consistent, high-quality solutions over time.